Page 3 - Gulf Consensus

CONSENSUS RECOMMENDATIONS FOR THE MANAGEMENT OF RRMS

CLASSIFYING DISEASE AT FIRST PRESENTATION

Patients with
Patients with
active MS without Patients with rapidly evolving
highly active
indicators of poor disease severe RRMS
prognosis

• One relapse in the last 1 • Patients with at least • At least one disabling
year, or two relapses in two relapses in the relapse (defined in
the last 2 years previous year Box 1) with impact
• No poor prognostic • And more than nine T2 on EDSS score (i.e.
indicators lesions, or ≥1 Gd+ lesion residual disabilities)
• This category replaces without an impact on or with MRI lesions in
the ‘low’ or ‘mild’ EDSS (i.e. no residual strategic prognostic
disease group usually disabilities after steroid areas (spinal cord,
used in disease activity treatment) cerebellum, brain stem)
classifications or poor prognostic
factors

Affects the patient’s social life Affects the patient’s activities of daily
or occupation, or is otherwise living as assessed by an appropriate
considered disabling by the patient. method.
Box 1. NHS England
definition of a
disabling MS relapse
Affects motor or sensory function
sufficiently to impair the capacity or Needs treatment/hospital admission.
reserve to care for themselves or others.